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Unlike systemic fat burners, which often lead to overstimulation of the nervous system, AOD-9604 acts at the cellular level, sending a signal directly to adipocytes (fat cells) ordering them to release stored fatty acids

doi:10.1073/pnas.62.2.461

Importantly, animals were singly housed to eliminate the exchange and cross-contamination of intestinal microbiomes, a factor that potentially biases studies with group-housed animals by minimizing microbiome variations for co-housed animals within a cohort

Mechanism of Action AOD9604 has been investigated for its interaction with beta-3 adrenergic receptor pathways in adipose tissue

For severe cases, a bigger dose might be given first, followed by smaller doses later