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Chrysin suppresses renal carcinogenesis via amelioration of hyperproliferation, oxidative stress and inflammation: plausible role of NF-B

Timing & therapeutic window Ferroptotic cell death in acute cardiac injury occurs within a narrow time frame, making the timing of intervention critical

Limit test studies failed to establish an LD50, indicating exceptionally low acute toxicity even at very high doses

This suggests that the effects of MG extend beyond binding to GSH and involve the inhibition of GSH resynthesis and enzymes that play key roles in its synthesis, thereby promoting ferroptosis