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This inflammation can lead to pigmentation issues, particularly in individuals prone to post-inflammatory hyperpigmentation

[1] Catalytic mechanism of phosphopentose isomerase The catalytic mechanism of phosphopentose isomerase resembles that of phosphohexose isomerase (EC 5.3.1.9), a glycolytic enzyme

Cell (2019) 179(2):292311

This study provides an early report of the loss of glial cells within the PFC of patients with mood disorders, consistent with the hypothesized glutamate abnormalities in these disorders