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Description

Models relevant to COPD (TGF-) play a crucial role as an inducer of ECM, mimicking the airway remodeling found in patients

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ISH probes were prepared by in vitro transcription with DIG RNA Labeling Mix (Roche Applied Science, #11277073910) or Fluorescein RNA Labeling mix (Roche Applied Science, #11685619910) and T7 polymerase (Promega, #P2075), T3 polymerase (Roche Applied Science, #11031163001) or SP6 polymerase (Roche Applied Science, #10810274001)

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This leads to the formation and deposition of urate monosodium crystals within soft tissues

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