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10.1016/j.abb.2020.108461 13 BoucherJ

GDNF promotes mitochondrial cristae membrane remodeling, enhancing oxidative phosphorylation coupling efficiency and ATP production, a mechanism validated in in vitro dopaminergic neuron cultures [74]

And CD4 + CD25 + T cells effectively inhibited colonic effector T cell activity and the production of Th1 (interferon (IFN)-, IL-2) and Th2 (IL-5, IL-13) cytokines in vitro, while the frequency of Treg cells in the inflammatory area increases with the increase of active UC disease activity [68, 69]

EA and its derivatives distribute across muscle, adipose tissue, heart, and lungs (103), where they persist for 2448 hours due to enterohepatic recycling (104, 105)