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Diabetic Nephropathy Diabetic nephropathy (DN), also known as diabetic kidney disease (DKD) [36,37,38], is a major cause of CKD and end-stage kidney failure in diabetic patients [39,40,41]

There was no basal level difference in MDA levels in IB3-1 and C38 (Fig

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Thus, while both toxin models capture essential elements of demyelination-associated activation, neither fully recapitulates the spectrum of microglial heterogeneity present in human disease