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During childhood, formation of bladder diverticuli may occur and skeletal changes such as exostoses at sites of tendon insertion, also called occipital horns, are typical

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It is believed this is because the smoke causes a 'hardy' sub-population in the bugs to emerge, called small colony variants

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For our observed MD of -1.47% in FMD to be statistically significant, we have calculated that at 90% power, the required minimum sample size would be approximately 328 (164 in the exclusive e-cigarette group, and 164 in the non-use group)