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Demand declined after the Surgeon Generals report in 1964 linked cigarettes to lung cancer, and continued to fall after the Master Settlement Agreement in 1998 restricted tobacco advertising and marketing

Especially in the last decade, cigarette shipment volumes have been in decline as smokers in developed markets have increasingly quit and a growing percentage of individuals in younger generations have been reluctant to start in the first place

Government-led education on e-cigarette products and their role in smoking cessation is essential

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There are, however, no formal screening tests for oropharyngeal or anal cancers