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Nicotine could contribute to this progression by aggravating vasoconstriction, although other tobacco smoke toxins are also likely to be contributing to progressive vascular injury. In laymans terms this tells us that nicotines impact as a vasoconstrictor (shrinking blood vessels which increases blood pressure) can contribute, alongside the other chemicals in cigarette smoke, to more severe conditions brought about by prolonged hypertension

Additionally, resin can collect at the end of a blunt if its not dried properly before smoking, or if it contains weed not cured properly, and that could get on your teeth

That's why batteries should also be carried in your hand luggage

Bommele J, Hopman P, Walters BH, Geboers C, Croes E, Fong GT, et al

While ACEA led to decreased AhR expression, AM251 led to the opposite and, thus, CYP1A1 induction (Solio et al., 2022)