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These inflammatory cells, factors, and mediators interact to form a complex network that stimulates mucous cell metaplasia, mucus secretion, fibroblast growth and extracellular matrix protein (ECM) synthesis, airway constriction and induces AHR and airway remodeling 5-9 .In recent years, studies have found that Th17 is also essential in the pathogenesis of asthma and is closely related to the recruitment of airway neutrophils 10

However, although it may be true that marijuana smoke deposits more tar into a smoker's lungs than tobacco smoke, the above-displayed photograph does not accurately depict the difference in overall harm caused to a tobacco smoker's lungs versus a marijuana smoker's lungs

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There is also a rising adoption of lower-risk substitutes, ongoing product innovation, and advantageous regulatory frameworks for smoke-free goods, all contributing to the region's faster market expansion

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