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They added that it cannot be determined whether e-cigarette experimentation leads to regular smoking. In the paper, the authors argue that to fully explore the association between e-cigarette use and smoking, larger cohort studies running over several years are needed

Imperial Tobacco Canada said tobacco regulations in Canada are already among the strictest in the world and more tobacco regulations will do nothing to further reduce smoking rates

Some consumers may shift to cheaper alternatives or reduce consumption due to higher costs

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But the following year, 1969, Ike and Tina had toured in the U.S