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The Adult Treatment Panel (ATP) III National Cholesterol Education Program (NCEP) has recommended that patients with atherosclerosis such as carotid artery disease be placed into the high-risk category, where the goal LDL is less than 100 mg/dL.16 The most recent American Heart Association (AHA) guidelines on secondary stroke prevention recommend even stricter goals: LDL lowering by 50% or more or an absolute LDL-cholesterol level goal of less than 70 mg/dL.17 These should apply to stroke or TIA patients with evidence of atherosclerosis (ie, large or small artery disease), those with an LDL-cholesterol level greater than 100 mg/dL, or those who have had coronary heart disease or its equivalents (Class I, Level of Evidence B)

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