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[email protected] Laxman, [email protected] Present address: Adhish S

Burr, M

MTHFR activity is greatly diminished in heterozygous 677C/T (-30%) and homozygous 677T/T (-65%) individuals compared to those with the 677C/C genotype (23)

Nature 487(7405):104108

He indicated a 40-50% alleviation in -oxidation in individuals with NASH, which was linked with elevated hepatic ROS and decreased indices of mitochondrial biosynthesis, mitosis, autophagy, fission, and fusion