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Overall, and as our findings also imply, the nature of tobacco effects may crucially depend on the plant material used, its preparation and ingredients added, as well as the context of administration (see also concept of set and setting in psychoactive plant use, Kabat-Zinn, 2003

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In 1937-8, actors including Gary Cooper, Joan Crawford, Clark Gable and Spencer Tracy, were each paid $10,000 (the equivalent to $146,000, or 80,000, in today's money) by American Tobacco to promote its Lucky Strike brand