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Academy of Breastfeeding Protocol #21 says that breastfeeding mothers who smoke or vape nicotine products may produce less breast milk and it may be less nutritional

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The propylene glycol in vape juice can cause dry mouth, which reduces saliva production and increases the risk of cavities and gum disease

In 2016, there was a ruling rejecting a case that sought to require an R rating for all but very limited depictions of tobacco use

Besides consideration of open or closed systems, other issues to consider when choosing a product include certification of adherence to Good Manufacturing Practices and whether the manufacturer provides product liability insurance