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These platelet-rich NPAs formed in situ and grew larger over time to occlude the lung microvasculature, leading to the development of pulmonary ischemia followed by the infiltration of NPAs and vascular leakage into the alveolar air space

Immediately after making their selection, the participants were informed that no packages would be mailed as the investigators did not want to endorse smoking

Overall, 34% of the participants were classified as current smokers

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