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As smoking provides short-term relief from withdrawal, and as the person thinks they feel better after a cigarette, this reinforces their smoking behaviour

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Figure 1 In those having HLA and non-HLA risk scores above the median levels of controls, the AF was 11.4% (95%CI: 6.8 to 15.9) and 12% (95%CI: 7.7 to 16.3), respectively