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Baseline data from the Whnau Pakari cohort (98% with a BMI 98th percentile, and 2% with a BMI 91st -98th percentile but with weight-related comorbidities at entry) found a higher prevalence of suboptimal dietary behaviours and significant differences in dietary intake when compared with national counterparts [41]

Some smokers roll their own blends, a practice that is more common in the countryside

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Therefore, in order to provide individualized therapy, physicians should inform patients about the interactions between smoking and metabolism of these drugs and consider smoking status in the development of the treatment plan, evaluating an increase in drug dosage