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38 Autophagy adapters are defined as proteins possessing both a ubiquitin-binding domain (UBD) that recognizes ubiquitin-tagged mitochondria and an LC3 interacting region (LIR) that interacts with ATG8 family proteins, which mainly includes sequestosome 1 (P62/SQSTM1), 39 neighbor of BRCA1 gene 1 (NBR1), 40 nuclear dot protein 52 (NDP52/CALCOCO2), 41 human T-cell leukemia virus type I binding protein 1 (TAX1BP1), 42 and optineurin (OPTN)

Clutch, Wes Welker, is stepping in as Mannings new slot receiver alongside WR Demaryius Thomas (94 receptions, 1,434 yards, 10 TDs) and Eric Decker (85 grabs, 1,064 yards, 13 TDs)

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