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In addition, smokers were not more prone to negative treatment outcomes, although a trend was observed (adjusted odds ratio [OR] 1.24, 95% confidence interval [CI] 0.911.70), and were more likely to be lost to follow-up, but this was also not significant (adjusted hazard ratio [HR] 2.09, 95% CI 0.894.94)

This is yet further evidence of the negative effects of smoking in pregnancy." The researchers stressed that their research was a pilot study and that larger studies were needed to confirm and further understand the relationship between maternal smoking, stress, depression and fetal development

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