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Food and Drug Administration (FDA) and Director of the FDAs Center for Tobacco Products wrote in 2017: Nicotine, though not benign, is not directly responsible for the tobacco-caused cancer, lung disease, and heart disease that kill hundreds of thousands of Americans each year . Tobacco smoke contains more than 6,000 chemicals, nearly 100 of which have been classified by public health agencies as harmful or potentially harmful constituents

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Over time, cigarette smoke irritates the airways and gradually reduces the bodys ability to oxygenate itself efficiently

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