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Alkali: Examples include sodium hydroxide (lye), calcium hydroxide (lime, cement, plaster), and ammonia

However, it is important to understand that tobacco use causes a number of cancers including head and neck cancers, throat cancers such as pharyngeal or laryngeal cancer, and oral cavity cancers such as tongue cancer

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Nicotine salt formulations, with a pH buffer of 5.0-5.5, allow nicotine concentrations of up to 50 milligrams per milliliter without causing throat irritation

Traditional NRT products (patches, gum, lozenges) are licensed medical devices with clinical cessation claims, regulated and approved by bodies like the FDA and EMA