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In this study, second-generation e-cigarettes were used, eliciting similar circulating nicotine concentrations to combustible tobacco, suggesting that other non-nicotine elements may be the primary cause of vascular dysfunction [116]

The answer lies in the ingredients: Native cigarettes are often positioned as simpler, additive-free products, while commercial cigarettes from big tobacco companies typically include a long list of chemicals designed to enhance flavour, extend shelf life, and intensify nicotine delivery

A 2023 study from Roswell Park, published in Thorax , examined the effects of CBD aerosols on mice and human cells