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Furthermore, nicotine is not only significantly decreasing the testicular activity of androgenic enzymes including testicular steroidogenic acute regulatory (StAR) protein resulting in decreased intratesticular and plasma testosterone and gonadotropin concentrations, but also reduced the testicular levels of glutathione, activities of antioxidative enzymes and mitochondrial membrane potential in testicular cells

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Primary cigarette making machines constitute the production core, converting processed tobacco into continuous cigarette rods, cutting them to length, and performing quality monitoring

16 Urbanicity, which was only available at W1, was also included as a covariate