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Nicotine disrupts normal body functions, precipitating chronic conditions and elevating the risk of serious diseases

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A systematic review published in 2022 in the Journal of Oral Pathology & Medicine revealed that factors like cytotoxicity (cell damage), oxidative stress (too many free radicals in the body), and genotoxicity (damage to DNA) were present in the head, neck, and oral cells of participants exposed to e-cigarettes

We hypothesise that a range of clinical events, including events related to obstructive airway diseases, previously studied teachable moments and diagnoses, and the onset of medication or care programmes related to treatment (or prevention) of highly prevalent comorbidities, are associated with a higher likelihood of smoking cessation attempts.