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6 Pharmacological Effects Polycyclic aromatic hydrocarbons from smoke inhalants induce cytochrome p450 and UDP-glucuronosyltransferase systems, thereby increasing the metabolism of opioids, benzodiazepines, propofol, most neuromuscular blockers, and volatile anesthetics

However, the CDC warns that while eliminating smoking in indoor spaces fully protects nonsmokers from exposure to secondhand smoke, no air purifier or conventional ventilation system can fully eliminate exposure of non-smokers to secondhand smoke

The USPSTF concludes that the evidence on pharmacotherapy interventions for tobacco smoking cessation in pregnant persons is insufficient because few studies are available, and the balance of benefits and harms cannot be determined

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Nicotine replacement therapy (NRT) like patches or gum is generally considered a safer alternative to smoking while breastfeeding because they don't involve inhaling smoke and toxins