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100% additive-free natural tobacco certified under USDA standards." Ad found in:Blender: May 2004Food & Wine: March 2004

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However, the exclusion of e-commerce retailers from these programs can undermine their impact," said principal investigator Eric Leas, PhD, MPH, an assistant professor at the Herbert Wertheim School of Public Health and Human Longevity Science at UC San Diego and director of the Tobacco E-commerce Lab

That said, there isnt enough extensive research on humans to provide a clear answer