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one such mechanism is via generation of carbon monoxide (a pharmacologically active neurotransmitter) upon metabolism of CBD

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Overdose also carries the risk of: Somnolence Tachycardia Disorientation Acute confusion acute psychosis Hyperglycemia Hypokalemia Hypertension Nausea, vomiting Amnesia, which may be prolonged Metabolic acidosis Myoclonic generalized seizures, rhabdomyolysis Renal failure Liver failure Intermittent apnea Cardiac arrhythmias, ECG changes There is also a small risk of acute myocardial infarction and cardiovascular collapse

While further research is needed to fully understand the relationship between smoking and testosterone levels, current evidence suggests a clear association between smoking and reduced testosterone in men