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1 Due to these uncertainties, a systematic review aimed to comprehensively assess current literature to determine whether MSDP has a direct effect on the development of teeth, focusing on anomalies such as deviations in root and crown shape, tooth number, hard tissue mineralization, and eruption patterns. 1 The Review The research question posed for this systematic review was What is the effect of smoking during pregnancy on the occurrence of dental development conditions in offspring when compared to non-smoking controls? 1 The study designs included in the review were observational studies, including cross-sectional, longitudinal/cohort, and case-control studies