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It also competitively blocks the binding of nicotine, so even if you do smoke, you wont feel as much of an effect

Diacetyl, in particular, is notorious for causing bronchiolitis obliterans, a debilitating lung disease more commonly known as popcorn lung. This irreversible condition leads to scarring in the tiny airways of the lungs, causing chronic coughing, wheezing, and severe shortness of breath

In other terms, the earlier stages (0 and I) tend to have a better prognosis due to a contained tumor within the lungs, while later stages (II, III, IV) have a poor prognosis

Compared with cigarette smoke, the effects of ECs on OA are still less clear and need more direct study

[52] in 1994, seven tobacco executives stated that nicotine was not addictive while on oath before the US Congress