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Nicotine was not consumed for recreation, it was tied to tradition, healing, and the natural world

Archived from the original on 4 January 2017

The Food and Drug Administration plans to ban the sale of fruity flavors in cartridge-based e-cigarettes, but the restriction wont apply to tank vaping systems commonly found at vape shops, according to people familiar with the matter

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Critically for addiction, nicotine stimulates dopamine release in the brains reward pathways (mesolimbic system), signaling pleasure and reinforcing drug taking behavior