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Among adults who meet the criteria for SUDwhich may include symptoms like increased tolerance, repeated attempts to quit or control use, or social problems related to use--95% did not seek treatment and didnt think they needed it

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For instance, it has been shown that cigarette smoke exposure of these cultures recapitulates many of the gene expression changes induced by smoking in human airway biopsies [45]

The idea that occasional use is harmless represents another myth unsupported by medical evidence