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Lets use some examples to make it clearer

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Hajek added, population data show that e-cigarettes have helped a large number of smokers quit, but there have been only a few experimental studies so far. In fact, the 2 randomized clinical trials looking at the effectiveness of e-cigarettes for smoking cessation that have been published to date both reported only modest cessation rates with e-cigarette use relative to placebo

The change takes effect in September, though young adults serving in the armed forces and those born before August 31, 2001, are exempt

Because cigarette beetles are found in our food supply, only properly trained professionals should treat infestations