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Physiologic and performance effects Amphetamines increase dopamine/norepinephrine release and inhibit their reuptake, leading to central nervous system (CNS) stimulation Amphetamines seem to enhance athletic performance in anaerobic conditions 39 40 Improved reaction time Increased muscle strength and delayed muscle fatigue Increased acceleration Increased alertness and attention to task 1 2 3 Molecular Neuropharmacology: A Foundation for Clinical Neuroscience (2nd ed.)