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Indeed, according to most patients judgment, quitting smoking has hardly ever any impact on the clinical course of CH

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The trend towards higher G-CSF levels that we observed in smokers has been reported previously 37 and is of potential import since the administration of this cytokine to humans has been shown to increase both granulocytes and monocytes 38 and thus may be at least partially responsible for the increase we see in these white blood cells in smokers

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