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The Merck drug Vioxx was a miracle pain relieveruntil researchers estimated that it was associated with as many as 140,000 excess cases of heart disease

Nature Reviews Neuroscience, 11(6), 389-401

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This suggests that e-cigarette commercials and promotion are not problematic from a smoking-cue standpoint unless they include visual depictions of people vaping e-cigarettes that have that visual similarity to traditional cigarettes, said Maloney

However, growing evidence increasingly challenges these assertions