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At a dose of 2 mg/kg in animal models, apigenin demonstrated significant anxiolytic activity across multiple testing paradigms, including the elevated plus-maze, hole board, and mirrored chamber tests, without sedative effects at therapeutic doses.7 A separate study confirmed that damiana extracts produced anxiolytic effects comparable to diazepam but without the cognitive impairment associated with pharmaceutical benzodiazepines.8 Flavor profile: Warm, slightly spicy, with subtle bitter notes reminiscent of chamomile and dried fig

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doi:10.1080/14622200802239132