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The Koziel group predominantly used a rapid multidimensionalgas chromatographymass spectrometryolfactometry (MDGC-MS-O) based odorant-prioritization screening approach, while the Oswald group used a two-dimensional gas chromatography method with three detectors running simultaneously: a time-of-flight mass spectrometer (TOF-MS), flame ionization detector (FID) and a sulfur chemiluminescence detector (SCD)

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[53] found in a cohort of adolescents and young adults with pediatric-onset CKD, that chronic e-cig use (at least 1 year) was significantly associated with progression of CKD severity (rise in proteinuria, decline in eGFR)