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The hit is present from the first puff, peaks around puffs 47, and tapers gently at the end without an abrupt drop

I cases of low blood sugar, it may become hard to distinguish between tobacco craving and sugar craving

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The authors highlight that from the time clozapine entered the New Zealand market, 7691 people were started on the drug, of which .47% developed serious CIGH, and in Australia 35,441 individuals were prescribed clozapine and .35% developed severe CIGH