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Cannabis use: Can negatively impact the developing brain May be linked to depression, especially for heavy users Can lead to addiction, also known as cannabis use disorder Nicotine addiction: Can harm the developing brain May make young people more susceptible to addiction later in life Can increase stress and intensify symptoms of depression and anxiety Young people may turn to nicotine and cannabis to deal with stress, not realizing it can make them feel worse Despite a widespread belief that nicotine use can reduce stress, research has established that nicotine addiction can worsen mental health symptoms