herbert a. gilbert smokeless non-tobacco cigarette 1963 patent In 1963, filed a for “a safe and harmless means for and method of smoking.” An Interview with the Inventor

As the dopamine level drops, the smoker feels depressed and lights the next cigarette or cigar to regain the heightened sense of pleasure and well-being

The map was finally transformed to Fisher Z values, so that maps across participants could be averaged and compared

The experience is quite unpleasant

You don't want to cut them wet, and you don't want to rip them

Our analysis of sight, sound, and touch don't pass through the same region of the brain, meaning smell in particular can transport us to memories we didn't even know we had: catching the aroma of a certain carpet cleaner might take us to our third grade classroom, a particular food to a forgotten childhood friend's house, and the fresh plastic of a new CD case to a long-closed Tower Records