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In hepatocellular carcinoma (HCC) cells, ketoconazole downregulates the expression of COX2, thereby triggering PINK1-Parkin-mediated mitophagy to enhance apoptosis, downregulate BCL2, BCL-XL and MCL1 and upregulate BAX and BAK [25] (Fig

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She has also trained over 2,000 Denton County volunteers, from ages nine to ninety, to assist local law enforcement in wide area search and rescue, crime scene preservation, and sheltering animals during disaster

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