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Combined Mainstream and Sidestream Smoke (CMSS) exposure causes death of 41,000 American adult non-smokers every year (King et al

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The agency is tasked with determining whether these products have a benefit to adult smokers sufficient to overcome the public health threat posed by the well-documented, alarming levels of youth use of such products. Flavored ENDS products are extremely popular among youth, with over 80% of e-cigarette users between ages 12 through 17 using one of these products, said Mitch Zeller, director of the FDAs Center for Tobacco Products