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(See : .) DOSAGE AND ADMINISTRATIONMultiple Sclerosis An acute myopathy has been observed with the use of high doses of corticosteroids, most often occurring in patients with disorders of neuromuscular transmission (e.g., myasthenia gravis), or in patients receiving concomitant therapy with neuromuscular blocking drugs (e.g., pancuronium)

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This limitation underscores the need for further studies to elucidate these underlying mechanisms