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This is because of the health dangers involved

Denoting the rsfMRI data of one voxel by x = [ x 1 , x 2 , , x N ], where N is the number of acquisitions, SampEn calculation starts with forming a series of vector sequences, each with m consecutive points extracted from x : u i = [ x i , x i +1, , x i + m 1], where i = 1( N m + 1), and m is the pre-defined window size (3, as stated above)

These machines are engineered for ease of use, with clear instructions to guide even beginners through the process