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Use with caution in patients with a current diagnosis or prior history of constipation, urinary retention, clinically significant prostatic hypertrophy, or other conditions in which anticholinergic effects can lead to significant adverse reactions

The association was also adjusted for self-reported and hospital diagnosed chronic obstructive pulmonary disease (COPD) and chronic pulmonary infections (definitions in eTable 3) at baseline, which may be important confounding factors [33, 34]

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Simpsons breakdown almost perfectly adheres to cigarette sales data collected by Attain