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"The whole mission is to decrease harm from smoking, which is not from the nicotine per se, but all the carcinogens and other chemicals that are in tobacco smoke," said Lazarus, senior author on the study published in the journal Chemical Research in Toxicology

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Critical age windows in the impact of lifetime smoking exposure on respiratory symptoms and disease among ever smokers

Autoantibodies against oxidized-LDL in smokers Smoking is associated with increased levels of Autoantibodies against oxidized-LDL In smokers, low density lipoprotein (LDL) is more prone to oxidation due to an excessive presence of reactive ROS, leading to elevated levels of antibodies against oxidized LDL (anti-oxLDL Ab)

The trial saw hundreds of daily smokers given e-cigarette starter kits and offered advice, with smoking habits assessed six months later