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In addition, we solicited comments on the extent to which, in a scenario with a billing and payment code with multiple manufacturers, a single manufacturer that lacks reported ASP units could assume full rebate liability for the entire billing and payment code if the manufacturer's NDCs lack reported ASP units and were sold or marketed during the applicable calendar quarter

Similarly, efforts to genetically engineer NK cells are being pursued to better combat immunosuppression induced by cancer cells and the TME [11,12,13]

doi: 10.3389/fimmu.2025.1584577 Received 27 February 2025 Accepted 14 April 2025 Published 08 May 2025 Volume 16 - 2025 Edited by Shangfeng Gao, The Affiliated Hospital of Xuzhou Medical University, China Reviewed by Jinming Han, Capital Medical University, China Sonja Hochmeister, Medical University of Graz, Austria Yw Qin, Nantong University, China Updates Copyright 2025 Zhang, Zhang, Chai, Wang, Zhang and Chen

1 Long-term exposure to heavy metals can lead to a range of health issues, including cognitive impairment, hormonal imbalances, poor immune function, kidney, liver, and brain damage, and even age-related chronic diseases such as cancer, heart disease, and neurodegenerative diseases

In the context of brain injury in human cases, the generation of new neurons can aid in recovery and functional restoration