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Varenicline is the most effective monotherapy currently available a Cochrane network meta-analysis found it more than doubled sustained abstinence rates at 6 months follow-up, compared with placebo (risk ratio 2.88, 95% CI 2.403.47)

Early adoption was modest, largely confined to niche urban markets and tech-savvy early adopters, particularly in metropolitan areas like Johannesburg, Cape Town, and Durban

High Income Countries (HICs) have put in place potent price and non-price control measures, and the Tobacco Industry is shifting its marketing strategies to the Low and Middle Income Countries (LMICs) where tobacco control measures are absent, inadequate or weakly implemented

Youll spot these throughout the city, especially at the neon-lit watering holes that define street corners, like Le Progrs tabac bar in Le Marias

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