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Geriatric Use A combined single- and multiple-dose pharmacokinetic study demonstrated that the pharmacokinetics of 1 mg varenicline given once daily or twice daily to 16 healthy elderly male and female smokers (aged 6575 years) for 7 consecutive days was similar to that of younger subjects

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Although tobacco use has declined in many countries, efforts to reduce tobacco use need to continue, particularly in countries where the prevalence rate remains high